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Random
What you say when you do not really know what to say.
Bill: "hey look at that"
Ted: "what is up with that"
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The way you greet a friend when you are feeling a little bit retro and a little bit geeky.
What is up my brother?
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Asks what another has his attention on. What is he thinking about or busy with? "Up" in this case is using a slang definition from around the 1930s meaning: occupied with, busy with.
This question is often used to start conversations with.
When I called my friend he didn't seem happy so I asked him "What is up?". He said he was having trouble with his girl.
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What's new; What's going on? wussup
:What's really up?
:Nothing
The question often asked, when a foulness beyond belief emanates from where the sun don't shine.
When I first blew off in front of my future wife, she asked increduously, 'What died up there?'
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This is a combination of "what's goin on?" and "what's up?". I said this accidently the first time I talked to this guy on the phone. I was trying to be cool and confident but inside I was nervous as hell! LOL
When you haven't seen or talked to someone in a while you can say..."What's goin up?"
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What me up means, you asked someone to update or brief you about the current affairs or relevant local or global affairs.
I could not watch the news today, Can you what me up??